Publications

Osborne LC, Monticelli LA, Nice TJ, Sutherland TE, Siracusa MC, Hepworth MR, Tomov VT, Kobuley D, Tran SV, Bittinger K et al..  2014.  Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.. Science. 345(6196):578-82.

Osborne LC, Monticelli LA, Nice TJ, Sutherland TE, Siracusa MC, Hepworth MR, Tomov VT, Kobuley D, Tran SV, Bittinger K et al..  2014.  Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.. Science. 345(6196):578-82.

Osborne LC, Monticelli LA, Nice TJ, Sutherland TE, Siracusa MC, Hepworth MR, Tomov VT, Kobuley D, Tran SV, Bittinger K et al..  2014.  Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.. Science. 345(6196):578-82.

Osborne LC, Monticelli LA, Nice TJ, Sutherland TE, Siracusa MC, Hepworth MR, Tomov VT, Kobuley D, Tran SV, Bittinger K et al..  2014.  Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.. Science. 345(6196):578-82.

Kelsen JR, Dawany N, Moran CJ, Petersen B-S, Sarmady M, Sasson A, Pauly-Hubbard H, Martinez A, Maurer K, Soong J et al..  2015.  Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease.. Gastroenterology. 149(6):1415-24.

Bergstrom KSB, Morampudi V, Chan JM, Bhinder G, Lau J, Yang H, Ma C, Huang T, Ryz N, Sham HPan et al..  2015.  Goblet Cell Derived RELM-β Recruits CD4+ T Cells during Infectious Colitis to Promote Protective Intestinal Epithelial Cell Proliferation.. PLoS Pathog. 11(8):e1005108.

Bergstrom KSB, Morampudi V, Chan JM, Bhinder G, Lau J, Yang H, Ma C, Huang T, Ryz N, Sham HPan et al..  2015.  Goblet Cell Derived RELM-β Recruits CD4+ T Cells during Infectious Colitis to Promote Protective Intestinal Epithelial Cell Proliferation.. PLoS Pathog. 11(8):e1005108.

Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P et al..  2015.  Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.. Nature. 519(7542):242-6.

Brestoff JR, Artis D.  2015.  Immune regulation of metabolic homeostasis in health and disease.. Cell. 161(1):146-60.

Kelsen JR, Baldassano RN, Artis D, Sonnenberg GF.  2015.  Maintaining intestinal health: the genetics and immunology of very early onset inflammatory bowel disease.. Cell Mol Gastroenterol Hepatol. 1(5):462-476.

Monticelli LA, Buck MD, Flamar A-L, Saenz SA, Wojno EDTait, Yudanin NA, Osborne LC, Hepworth MR, Tran SV, Rodewald H-R et al..  2016.  Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.. Nat Immunol. 17(6):656-65.

Howitt MR, Lavoie S, Michaud M, Blum AM, Tran SV, Weinstock JV, Gallini CAnn, Redding K, Margolskee RF, Osborne LC et al..  2016.  Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut.. Science. 351(6279):1329-33.

Hussain M, Borcard L, Walsh KP, Rodriguez MPena, Mueller C, Kim BS, Kubo M, Artis D, Noti M.  2017.  Basophil-derived IL-4 promotes epicutaneous antigen sensitization concomitant with the development of food allergy.. J Allergy Clin Immunol.

Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour R-EE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D et al..  2017.  The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.. Nature. 549(7672):351-356.

Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour R-EE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D et al..  2017.  The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.. Nature. 549(7672):351-356.

J Blander M, Longman RS, Iliev ID, Sonnenberg GF, Artis D.  2017.  Regulation of inflammation by microbiota interactions with the host.. Nat Immunol. 18(8):851-860.

Jacob V, Crawford C, Cohen-Mekelburg S, Viladomiu M, Putzel GG, Schneider Y, Chabouni F, OʼNeil S, Bosworth B, Woo V et al..  2017.  Single Delivery of High-Diversity Fecal Microbiota Preparation by Colonoscopy Is Safe and Effective in Increasing Microbial Diversity in Active Ulcerative Colitis.. Inflamm Bowel Dis. 23(6):903-911.

Moriyama S, Brestoff JR, Flamar A-L, Moeller JB, Klose CSN, Rankin LC, Yudanin NA, Monticelli LA, Putzel GGarbès, Rodewald H-R et al..  2018.  β-adrenergic receptor-mediated negative regulation of group 2 innate lymphoid cell responses.. Science. 359(6379):1056-1061.

Campbell L, Hepworth MR, Whittingham-Dowd J, Thompson S, Bancroft AJ, Hayes KS, Shaw TN, Dickey BF, Flamar A-L, Artis D et al..  2019.  ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.. J Exp Med. 216(12):2714-2723.

Chu C, Murdock MH, Jing D, Won THyung, Chung H, Kressel AM, Tsaava T, Addorisio ME, Putzel GG, Zhou L et al..  2019.  The microbiota regulate neuronal function and fear extinction learning.. Nature. 574(7779):543-548.

Moeller JB, Leonardi I, Schlosser A, Flamar A-L, Bessman NJ, Putzel GGarbès, Thomsen T, Hammond M, Jepsen CS, Skjødt K et al..  2019.  Modulation of the fungal mycobiome is regulated by the chitin-binding receptor FIBCD1.. J Exp Med. 216(12):2689-2700.

Nagashima H, Mahlakõiv T, Shih H-Y, Davis FP, Meylan F, Huang Y, Harrison OJ, Yao C, Mikami Y, Urban JF et al..  2019.  Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation.. Immunity.

Mahlakõiv T, Flamar A-L, Johnston LK, Moriyama S, Putzel GG, Bryce PJ, Artis D.  2019.  Stromal cells maintain immune cell homeostasis in adipose tissue via production of interleukin-33.. Sci Immunol. 4(35)

Flamar A-L, Klose CSN, Moeller JB, Mahlakõiv T, Bessman NJ, Zhang W, Moriyama S, Stokic-Trtica V, Rankin LC, Putzel GGarbès et al..  2020.  Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity.. Immunity.

Zhang W, Lyu M, Bessman NJ, Xie Z, Arifuzzaman M, Yano H, Parkhurst CN, Chu C, Zhou L, Putzel GG et al..  2022.  Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection.. Cell. 185(22):4170-4189.e20.