Publications

Won THyung, Arifuzzaman M, Parkhurst CN, Miranda IC, Zhang B, Hu E, Kashyap S, Letourneau J, Jin W-B, Fu Y et al..  2025.  Host metabolism balances microbial regulation of bile acid signalling.. Nature. 638(8049):216-224.

Hou X, Artis D.  2025.  Neuro-immune cell interactions in the regulation of intestinal immune homeostasis.. Curr Opin Gastroenterol. 41(1):38-45.

Zaiss DMW, Pearce EJ, Artis D, McKenzie ANJ, Klose CSN.  2024.  Cooperation of ILC2s and TH2 cells in the expulsion of intestinal helminth parasites.. Nat Rev Immunol. 24(4):294-302.

Arifuzzaman M, Won THyung, Yano H, Uddin J, Emanuel ER, Hu E, Zhang W, Li T-T, Jin W-B, Grier A et al..  2024.  Dietary fiber is a critical determinant of pathologic ILC2 responses and intestinal inflammation.. J Exp Med. 221(5)

Emanuel E, Arifuzzaman M, Artis D.  2024.  Epithelial-neuronal-immune cell interactions: Implications for immunity, inflammation, and tissue homeostasis at mucosal sites.. J Allergy Clin Immunol. 153(5):1169-1180.

Liao Y, Gao IH, Kusakabe T, Lin W-Y, Grier A, Pan X, Morzhanaeva O, Shea TP, Yano H, Karo-Atar D et al..  2024.  Fungal symbiont transmitted by free-living mice promotes type 2 immunity.. Nature. 636(8043):697-704.

Troch KF, Jakob MO, Forster PM, Jarick KJ, Schreiber J, Preusser A, Guerra GM, Durek P, Tizian C, Sterczyk N et al..  2024.  Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells.. Nat Commun. 15(1):10566.

Li T-T, Chen X, Huo D, Arifuzzaman M, Qiao S, Jin W-B, Shi H, Li XV, Iliev ID, Artis D et al..  2024.  Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology.. Cell Host Microbe. 32(5):661-675.e10.

Arifuzzaman M, Collins N, Guo C-J, Artis D.  2024.  Nutritional regulation of microbiota-derived metabolites: Implications for immunity and inflammation.. Immunity. 57(1):14-27.

Mayassi T, Li C, Segerstolpe Å, Brown EM, Weisberg R, Nakata T, Yano H, Herbst P, Artis D, Graham DB et al..  2024.  Spatially restricted immune and microbiota-driven adaptation of the gut.. Nature. 636(8042):447-456.

Li Z, Ma R, Tang H, Guo J, Shah Z, Zhang J, Liu N, Cao S, Marcucci G, Artis D et al..  2024.  Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death.. Cell. 187(3):624-641.e23.

Jin W-B, Li T-T, Huo D, Qu S, Li XV, Arifuzzaman M, Lima SF, Shi H-Q, Wang A, Putzel GG et al..  2022.  Genetic manipulation of gut microbes enables single-gene interrogation in a complex microbiome.. Cell. 185(3):547-562.e22.

Zhang W, Lyu M, Bessman NJ, Xie Z, Arifuzzaman M, Yano H, Parkhurst CN, Chu C, Zhou L, Putzel GG et al..  2022.  Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection.. Cell. 185(22):4170-4189.e20.

Arifuzzaman M, Won THyung, Li T-T, Yano H, Digumarthi S, Heras AF, Zhang W, Parkhurst CN, Kashyap S, Jin W-B et al..  2022.  Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation.. Nature. 611(7936):578-584.

Tsou AM, Yano H, Parkhurst CN, Mahlakõiv T, Chu C, Zhang W, He Z, Jarick KJ, Zhong C, Putzel GG et al..  2022.  Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces.. Nature. 611(7937):787-793.

Jarick KJ, Topczewska PM, Jakob MO, Yano H, Arifuzzaman M, Gao X, Boulekou S, Stokic-Trtica V, Leclère PS, Preußer A et al..  2022.  Non-redundant functions of group 2 innate lymphoid cells.. Nature. 611(7937):794-800.

Chung H, Parkhurst CN, Magee EM, Phillips D, Habibi E, Chen F, Yeung BZ, Waldman J, Artis D, Regev A.  2021.  Joint single-cell measurements of nuclear proteins and RNA in vivo.. Nat Methods. 18(10):1204-1212.

Klose CSN, Artis D.  2020.  Innate lymphoid cells control signaling circuits to regulate tissue-specific immunity.. Cell Res. 30(6):475-491.

Campbell L, Hepworth MR, Whittingham-Dowd J, Thompson S, Bancroft AJ, Hayes KS, Shaw TN, Dickey BF, Flamar A-L, Artis D et al..  2019.  ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.. J Exp Med. 216(12):2714-2723.

Chu C, Murdock MH, Jing D, Won THyung, Chung H, Kressel AM, Tsaava T, Addorisio ME, Putzel GG, Zhou L et al..  2019.  The microbiota regulate neuronal function and fear extinction learning.. Nature. 574(7779):543-548.

Rankin LC, Artis D.  2018.  Beyond Host Defense: Emerging Functions of the Immune System in Regulating Complex Tissue Physiology.. Cell. 173(3):554-567.

Rankin LC, Artis D.  2018.  Beyond Host Defense: Emerging Functions of the Immune System in Regulating Complex Tissue Physiology.. Cell. 173(3):554-567.

Veiga-Fernandes H, Artis D.  2018.  Neuronal-immune system cross-talk in homeostasis.. Science. 359(6383):1465-1466.

Howitt MR, Lavoie S, Michaud M, Blum AM, Tran SV, Weinstock JV, Gallini CAnn, Redding K, Margolskee RF, Osborne LC et al..  2016.  Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut.. Science. 351(6279):1329-33.

Artis D, Spits H.  2015.  The biology of innate lymphoid cells.. Nature. 517(7534):293-301.