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Neuronal regulation of group 2 innate lymphoid cells and type 2 inflammation.

TitleNeuronal regulation of group 2 innate lymphoid cells and type 2 inflammation.
Publication TypeJournal Article
Year of Publication2019
AuthorsMoriyama S, Artis D
JournalAdv Immunol
Volume143
Pagination1-9
Date Published2019
ISSN1557-8445
Abstract

Diverse infectious, inflammatory, and environmental stimuli induce type 2 inflammation in the body. Group 2 innate lymphoid cells (ILC2s) are potent producers of type 2 cytokines and play important roles in promoting type 2 inflammation. In addition to alarmins and other cytokines which are known to regulate ILC2 responses, emerging studies identified the regulation of ILC2s by the nervous system through neurotransmitter and neuropeptides. In this review, we highlight recent advances in the regulation of ILC2s and type 2 inflammation by the nervous system.

DOI10.1016/bs.ai.2019.08.001
Alternate JournalAdv. Immunol.
PubMed ID31607366